What strategic location did NSW seize to prevent General Noriega from fleeing?

The strategic location that was seized to prevent General Noriega from fleeing was Paitilla airfield. This airfield was vital because it represented one of the few escape routes available to Noriega during the U.S. military intervention in Panama. By securing this location, U.S. forces effectively cut off any possibility for him to escape by air, thereby isolating him and reducing his options for evading capture.

Other potential choices, while significant in the context of Panama's geography and military strategy, do not specifically pertain to blocking Noriega's escape route. Balboa Avenue and Coronado Beach, for example, do not have the same strategic impact regarding aerial escape routes that the Paitilla airfield had. The Panama Canal, although crucial for military and logistical operations, was not directly related to Noriega's immediate options for flight at that moment. Thus, the action taken at Paitilla airfield was critical in ensuring the successful apprehension of Noriega.